Diet & Intermittent Fasting

David SinclairUnclaimedDiet Protocol · 5 interventions

Diet & Intermittent Fasting

Diet Protocol · 5 interventions

Sinclair's plant-forward diet with 16:8 intermittent fasting. Philosophy: mild biological stress activates longevity pathways.

Diet

01Interventions5 interventions

Nutrition

5 interventions

01
Time-Restricted Eating
Dose & timing
Skip breakfast, often lunch too Daily
Activates AMPK and sirtuin survival pathways
^§Lifespan (2019)
02
Plant-forward diet
Dose & timing
Heavy on vegetables, mushrooms, pulses, whole grains Daily
"I eat a lot of plants and try to avoid eating other mammals"
^§Lifespan (2019)
03
Limited red meat
Dose & timing
Fish and occasional chicken; avoids red meat Daily · Ongoing
TMAO concern — will eat meat after workouts
^§Lifespan (2019)
04
Homemade probiotic yogurt
Dose & timing
2 spoonfuls with NMN + resveratrol Daily · Morning
Gut health + fat source for resveratrol absorption
^§Lifespan (2019)
05
No sugar, no refined carbs, minimal alcohol
Dose & timing
Strict avoidance Daily · Always
Metabolic health and longevity
^§Lifespan (2019)

Filed under

fastingplant-basedlongevity

02Citations1 links

01Lifespan (2019)Time-Restricted Eating

03Edit history1 editions

v1Current versionFebruary 18, 2026