Daily Supplement Stack
Supplement Protocol · 16 interventions
Huberman's core daily supplements plus sleep cocktail for testosterone, brain health, and recovery.
01Interventions
Supplements
16 interventions- 01Dose & timing400 mg Daily · Morning
Testosterone optimization — went from ~600 to high 700s ng/dL
- 02Dose & timing400-600 mg Daily · Morning, cycled 8-12 weeks on/off
Testosterone support (cycles and monitors blood work)
- 03Dose & timing2-3g EPA Daily
Cardiovascular and brain health
- 04
- 05Dose & timingStandard dose Daily
Cardiovascular health, calcium metabolism
- 06Dose & timing5g Daily
Cognitive and muscle benefits
- 07Multivitamin (Opti-Men)
Optimum Nutrition
Dose & timing1 pill DailyBaseline micronutrient coverage — taken for ~25 years
- 08Dose & timing~15 mg Daily
Testosterone and immune support (via Opti-Men)
- 09
- 10Dose & timing400-800 mg Daily with meal
Antioxidant and vascular health
- 11Dose & timing~1,100 mg Daily with food
Digestive support
- 12Dose & timing145 mg Daily before sleep
Sleep quality — crosses blood-brain barrier
- 13
- 14Dose & timing100-300 mg Daily before sleep
Relaxation without sedation (skip if vivid dreams)
- 15Dose & timing2g Daily before sleep, 3-4 nights/week
Sleep quality and recovery
- 16Dose & timing100 mg Daily before sleep, 3-4 nights/week
Calm nervous system for deeper sleep
02Citations
- 01Rhonda Patrick interview (Jun 2024)Tongkat Ali
- 02Kyle Gillett interview #2 (2023)Fadogia Agrestis
- 03Foundational Fitness Protocol (2022)Creatine Monohydrate
- 04MPMD interview (2023)Boron
- 05Toolkit for Sleep (2021)Magnesium L-Threonate
03Edit history
- v1Current versionFebruary 18, 2026